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學歷: |
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國立臺灣大學畜產學研究所
博士 |
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專長:
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1.
基改生物技術
2. 畜牧獸醫/生殖生理
3.
異種移植
4.生物安全性評估
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參加學術團體: |
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1. 中國畜牧學會(CSAS)
2.
中華民國實驗動物學會
3.
國際異種移植學會
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歷年發表報告: |
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A.
期刊論文
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Tu, C, Fu,
T. Sato, M. Hagihara, K. H. Lee, Y. C. Lee, C. N. Weng, R. Chu, K.
Tsuji, C. J. Lee. 1998. The expression of HLA-DP antigen on peripheral
blood mononuclear cells of HLA-DP transgenic pigs. Transplant. Proc.
30 (7A): 3502-3. (SCI; NSC86-2621-B-059-001 A21 and
NSC86-2621-B-059-002 A21)
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Tu, C. Fu,
K. Tsuji, K. H. Lee, R. Chu, T. J. Sun, Y. C. Lee, C. N. Weng, C. J.
Lee. 1999.
Generation of HLA-DP transgenic pigs for the study of
xenotransplantation. Int. Surg. 84:176-182. (SCI; NSC85-2321-B-059-013
A21, NSC85-2321-B-059-014 A21, NSC86-2621-B-059-001 A21, and
NSC86-2621-B-059-002 A21)
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杜清富,黃麗華,鄭登貴。1999。顯微注射反轉錄病毒轉染早期小鼠胚以產生基因轉殖小鼠。中國畜牧學會會誌。28:379-392。
Huang, H. W., T. Z. Liu, K. H. Lee, C. F. Tu, W. C. Lee,
T. Shimogiri, H. Mannen and S. S. O. Li. 2000. cDNA cloning of pig
testicular lactate dehydrogenase-C, thermal stablility of the
expressed enzyme, and polymorphism among strains. Gene 242:151-154.
(SCI)
Tu, C. Fu.,
S. L. Hsieh, J. M. Lee, L. L.Yang, T. Sato, K. H. Lee, C. N. Weng, S.
J. Mao, K. Tsuji, C. J. Lee. 2000. Successful generation of transgenic
pigs for human decay-accelerating factor and human leucocyte antigen
DQ. Transplant Proc. 32(5): 913-5. (SCI; NSC87-2313-B-059-014-, and
NSC88-2313-B-059 -011 A 21)
King, Y. T., W. C. Lee, M. S. Gao, J. L. Wang, C. F. Tu,
S. C. Wu and Y. H. Kuo. 2000. Synthesis of 60- and 72-kDa heat shock
proteins in early stage of porcine embryogenesis. Anim. Reprod Sci.
63: 221-229. (SCI)
Lee, J. M., C. F. Tu, K. Tsuji, Y. C. Lee, C. J. Lee.
2000.
The effective antigen presentation of human MHC on the lymphocyte of
HLA DPw4 transgenic pig: examination with xenogenic mixed lymphocyte
culture and primed lymphocyte test. Transplant. Proc.32: 2503-2504.
(SCI)
Hsu, P. N., H. H. Lin, C. F. Tu, N. J. Chen, K. M. Wu,
H. F. Tsai, S. L. Hsieh.
2001. Human FasL gene does not induce inflammation in pancreas but is
unable to protect islet graft from transplantation rejection in
pancreas-specific hFasL transgenic mice. J. Biol. Med. 8: 262-269.
(SCI; NSC89-2313-B-059-027-A21
杜清富、吳信志、楊平政、鄭登貴。2001。家畜基因轉殖技術與應用。中國畜牧學會會誌30:
37-43。(綜評)
杜清富、楊泠泠。2001。攜帶人類白血球表面抗原-DR(A1+B1)與人類壞死加速因子三基因轉殖小鼠之產製。中國畜牧學會會誌
30:129-140。
(NSC 85-2321-B-059-014-A21, NSC 88-2313-B-059-011-A21)
杜清富、顏重河、楊平政、翁仲男。2002。基因轉殖家畜作為生物反應器生產醫藥之技術。工程
75: 35-40。(綜說)
Lee, J. M..,# C. F. Tu,# P. W. Yang, K. H. Lee, K.
Tsuji, M. K. Tsai, R. J. Chen, C. Y. Hu, R. P. Hsieh, H. C. Tai, B. L
Chiang, C. N. Weng, Y. C. Lee, C. J. Lee. 2002. Reduction of
human-to-pig cellular response by alteration of porcine MHC with human
HLA DPw0401 exogenes.
Transplantation 73(2): 193-197. (SCI)
(equal contribution)
Juang, J. J*, C. F. Tu, C. H. Kuo, P. N. Hsu. 2002.
No protective effect of Fas-ligand transgenic islet on allogeneic
rejection.
Transplant. Proc. 34: 1456-1457. (SCI)
杜清富、劉明薰、郭有海。2003。以簡易玻璃化法冷凍保存基因轉殖小鼠之胚。中國畜牧學會會誌。32
(1): 33-42。
(NSC 85-2321-B-059-014-A21; NSC 86-2621-B-059-01- A21; NSC
89-2313-B-059-027-A21;91-EC-2-A-17-0454)
吳信志、鄭登貴、杜清富、顏重河、楊平政、翁仲男。2003。基因轉殖家畜生產醫藥蛋白質之研究與應用價值。生技產業
14(1):3-10。(綜說)
李坤雄、杜清富、吳信志、徐維荃。2003。一株小鼠胚幹細胞株可以例行產製表現綠色螢光且具高性腺遺傳能力小鼠。中畜會誌32
(2):143-154。
Tu, C. Fu., J. M. Lee, T. Sato, H. C. Tai., F. R. Lee, C. K. Yang, K.
Tsuji., C. J. Lee. 2003. Expression
of HLA-DQ in transgenic pigs. Transplant. Proc. 35: 513-515.
Lee, J. M., C. F. Tu, S. C. Huang, K. Tsuji, R. J. Chen,
C. Y. Hu, R. P. Hsieh, H. C. Dai, C. N. Weng, Y. C. Lee, C. J. Lee*.
2003. Attenuation of human–to-pig xenogenic cellular proliferation and
Th1 response by expressing the human MHC II DQ exogenes. On porcine
cells. Transplant. Proc. 35: 527-528. (SCI).
Lee, J. W., S. C. Wu, C. Tian, M. Barber, T. Hoagland, J.
Riesen, K. H. Lee, C. F. Tu, W. T. Cheng, X. Yang. 2003.
Production of cloned pigs by whole cell intracytoplasmic
microinjection. Biol. Reprod. 69(3): 995-1001.
杜清富*、黃桂芬、陳逸仲、林之任、吳信志、楊平政。2004。應用即時聚合酶連鎖反應法快速篩選吸血蛭抗凝血蛋白質基因轉殖仔豬。中畜會誌
33(4):289-300。
Wang, B. T., C.
F. Tu, L. J.Hsieh, H. C. Tai, Y. L. Chiu, J. M. Lee, S. J. Kuo,
K. Tsuji and C. J. Lee*. 2004. Detection of HLA transgenic pigs by
fluorescence in situ hybridization for future human
xenotransplantation. Xenotransplantation 11: 471-475.
Huang, S. Y.,
C. F. Tu,
S. H. Leu, y. h. kuo. 2004. Motility and fertility of alginate
encapsulated boar spermatozoa. Anim. Reprod. Sci
87:111-120.(SCI)
Chen, M. Y.,
C. F. Tu,
S. Y. Huang, J. H. Lin,
B. S. Tzang, H. L. Tsou, T. H. Hseu,
W. C. Lee*. 2005.
Augmenting thermotolerance in
primary skin fibroblasts from a transgenic pig with overexpressed
porcine HSP70.2. Asian-Australia J. Anim. Sci.
18(1):107-112.
Tu, C. F., C. Kuo,
J. Juang*.
2005.
Effects of heme oxygenase-1
transgenic islets on transplantation.
transplant. proc. 37:3463-3467. (SCI) 【所外合作論文】
Huang, S. Y., Y. H. Chen, S. H. Teng, I. C. Chen, L. L. Ho and
C. F. Tu.*, 2006. Protein expression of lymphocytes in HLA-DR
transgenic pigs by a proteomic approach. Proteomics 6(21):5815-5825.
(SCI, IF=6.088)
Lee, J. M., C. F. Tu, H. C. Tai, N. K. Chou, T. S. Yang,
C. N. Weng, Y. C. Lee and P. H. Lee*. 2006. The hDAF exogene protects
swine endothelial and peripheral blood mononuclear cells from
xenoreactive antibody mediated cytotoxicity in hDAF transgenic pigs.
Transplant. Proc. 38(7):2270-2272.
Lee K. H.*, C. k. Chuang.,
H. W. Wang, L. Stone, C. H. Chen, C. F. Tu. 2006.
Efficient and mass production of murine chimeric embryos by
coculturing denuded embryos and embryonic stem cells in Eppendorf
vials. Theriogenology. 67:228-237.
戴浩志、李章銘、周迺寬、杜清富、李伯皇。2007。異種移植:以乳糖轉移酶基因剔除豬為例。台灣醫學11(1):70-78。
杜清富。2007。誰說人面豬心不可能?科技加持基因轉殖豬加值。科學月刊。447
(3):189-193。
Chen, C. H., L. Stone, J. C.
Ju, W. T. Lien, M. S. Liu, C. F. Tu and K. H. Lee*.
2007. Generation
of cloned mice expressing enhanced green fluorescent protein by
activation stimuli combined with 6-dimethylaminopurine.
Reprod. Dom. Anim. (In press)
Lee, J. M.., C. F. Tu, H. C. Tai, N. K. Chou, C. N.
Weng, Y. C. Lee, C. J. Lee, P. H. Lee. 2008.
The impacts of human ABO blood groups on human xenoreactive
antibody-mediated cytotoxicity and the protective effect of human
decay accelerating factors (hDAF) exogene on the swine endothelium.
Transplant
Proc
(In press).
Tu, C. F.*,
H. C. Tai, C. m. Chen, T. T. Hung, J. M. Lee, T. S. Yang, C. H. Chen,
Y. L. Tseng, N. K. Chou, P. H. Lee. 2008.
Human Leukocyte Antigen-DR Matching Improved Skin Graft From
Ttansgenic Pigs to Accommodate in SCID Mice Reconstructed with Human
Peripheral Blood Mononuclear Cells.
Transplant
Proc
(In press).
Tai, H. C., C. F. Tu, L. L. Ho, Y. C. Chao, N. K. Chou,
J. M. Lee, T. S. Yuang, P. H. Lee, Y. B. Tang, K. J. 2008.
Long-Term Survival of HLA-DR Pig Skin in SCID Mice after
Reconstitution with Human PBMC and Short-Term Immunosuppression.
Transplant
Proc
(In press).
Yen C. H., C. K. Yang, C. S. Lin, I. C. Chen and C. F. Tu*.
2008.
Expression the synthetic Hirudin genes in transgenic Animals milk
driven by mammary-specific goat
b-casein
sequences.
Biotech. J. (Accepted).
杜清富、戴浩志、楊天樹、李章銘、曾堯麟、周迺寬、楊卿堯、莊景凱、翁仲男、李伯皇。2008。豬隻基因工程發展做為異種移植研究。台灣醫學。(Accepted)
Huang, S. Y.,
J. H. Lin,
Y. H. Chen, Shih-Hua Teng, W. T. K. Cheng, S. C. Wu* and
C. F. Tu*. 2008. Comparison of Protein Expression in the
Mammary Gland from Different Lines of Human Factor IX Transgenic and
Non-transgenic Pigs Using a Proteomic Approach.
Proteomics (Submitted).
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| B.
研討會論文 |
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杜清富、李俊仁。1999。豬器官供人類異種移植使用之展望:第二型人類白血球表面抗原基因轉殖豬之產製與分析。豬在生物醫學科技研發之應用研討會專輯
pp.11-14。台灣養豬科學研究所,竹南。
-
Tu,
C. F.,
Hsieh S. L., J. M. Lee, L. L. Yang ,T. Sato, K. H. Lee, C. N. Weng
, S. J. T. Mao, K. Tsuji, C. J. Lee. 1999. Successful generation of human decay
accelerating factor (hDAF) and human leucocyte antigenDQ (HLA-DQ)
transgenic pigs. 6th Congress of the Asian Society of Transplantation.
Suntec City, Singapore. p. 40.
-
Tu,
C. F., L. L. Yang , J. M. Lee , T. Sato , K.H. Lee, C.
N. Weng, S. J. T. Mao, K. Tsuji , C. J. Lee. 1999. The expression of HLA-DP antigen on
the organs and tissues of HLA-DP transgenic pigs. 6th Congress of the Asian Society of Transplantation. Suntec
City, Singapore. p. 311.
-
Lee,
C. J.,
C. F.Tu , J. M. Lee, I. H. Pan, K. H. Lee. 1999.
Recent development of organ transplantation in Taiwan. 6th Congress of
the Asian Society of Transplantation. Suntec City, Singapore. p. 69.
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Lee,
J. M.,
C. F. Tu , K. Tsuji, Y. C. Lee, C. J. Lee. 1999. The effective presentation of human MHC on the
leucocyte of HLA-DP w4 transgenic pigs: examination with xenogenic mixed
lyphocyte culture and primed lymphocyte test. 6th Congress of the Asian
Society of Transplantation. Suntec City, Singapore. p. 310.
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Tu,
C. F., S. L.Hsieh, J. M. Lee, L. L. Yang, T. Sato, K. H. Lee,
C. N. Weng, S. J. T. Mao, K. Tsuji, C. J. Lee. 1999. Successful generation of human decay
accelerating factor (hDAF) and human leucocyte antigenDQ (HLA-DQ)
transgenic pigs. 5th Congress of the International
Xenotransplantation Association. Nagoya, Japan. p. 35.
-
Lee,
J. M.,
C. F. Tu ,
K. Tsuji, Y. C. Lee, C. J. Lee. 1999.
The effective presentation of human MHC on the leucocyte of HLA-DP w4
transgenic pigs: examination with xenogenic mixed lyphocyte culture and
primed lymphocyte test. 5th Congress of the International
Xenotransplantation Association. Nagoya, Japan. p. 96.
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吳明憲、陳世平、林盈宏、洪榮偉、吳信志、楊天樹、劉琳琳、杜清富。1999。精胺酸對豬卵體外成熟與體外受精之影響。中畜會誌
28(增刊):146。
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林盈宏、黃三元、楊泠泠、張虹書、吳明憲、黃秀琴、金悅祖、洪榮偉、劉琳琳、李文權、杜清富。
1999。 熱緊迫蛋白90及70與豬卵體外成熟之關係。中畜會誌
28(增刊):147。
郭有海、劉明薰、連雯慈、吳信志、謝淑惠、杜清富。1999。簡易玻璃化法冷凍轉殖基因小白鼠胚。中畜會誌
28(增刊):170。
Kuo, Y. H., W. T. K. Cheng, C. F. Tu, S. C. Wu, H. T. Chen, S. H. Hsieh, S. Y. Huang.
2000. Motility and fertility of frozen semen from normal and
transgenic boars with or without transgene. Asian-Aus. J. Anim. Sci.
13 (Suppl.): 74.
Tu,
C. F.,
C. N. Weng, J. T. Mao. 2000. Clinical aspect of transgenic pigs. The 6th
Biomedical and Technology Symposium, R.O.C. pp. 22-25.
Tu,
C. F.,
H. L. Tsou, K. H. Lee, C. N. Weng, R. Chu. 2000. The application of
pig embryo transfer for transgenesis on xenotransplantation in Pig
Research Institute
Taiwan
. 11th Congress Fedration Asian Veterinary Associations,
Taipei
,
Taiwan
. p.290.
Tu,
C. F.,
S. C. Wu, T. S Yang, K. H. Lee, S. J.T. Mao, C. N. Weng, Y. H. Kou, W.
C. Lee, R. M.
Chu
, and W. T. K. Cheng. 2000. Progress of transgenic research in Pig
Research Institute
Taiwan
, The bilateral workshop on agricultural technology between
Taiwan
and
Canada
, pp.197-199.
Chen, S. Y., J. R. Mo, Y. F. Chung, S. Y. Huang, Y. H.
Lin, L. L. Liu, W. C. Lee, C.
F. Tu. 2000. The expression of porcine heat shock protein 70
and 90 during oocytes in vitro maturation. J. Chin. Soc. Anim. SCI. 29
(Suppl.): 159.
Tu,
C. F.,
J. M Lee, T. Sato, H. C. Tai, Y. F. Chung, F. R. Lee, P. W. Yang, K.
Tsuji, C. J. Lee. 2001. Integration and expression of HLA-DR
transgenic pigs. Xenoransplantation 8 (Suppl. 1): 84.
Chen, M. Y., B. S. Tzang, C. F. Tu, W. C. Lee. 2001. Production of transgenic pig
overexpressing heat shock protein 70.2. J. Chin. Soc. Anim. Sci. 30:
88 (Abstract).
Tu, C. F., J. M. Lee, T. Sato, H. C. Tai., F. R. Lee,
C. K. Yang, K. Tsuji., C. J. Lee. 2002.
Expression of HLA-DQ in transgenic pigs. 7th Congress of the Asian
Society of Transplantation.
New Delhi
,
India
. p.91.
Lee, J. M., C. F. Tu, S. C. Huang, K.
Tsuji, R. J. Chen, C. Y. Hu, R. P. Hsieh, H. C. Dai, C. N. Weng, Y. C.
Lee, C. J. Lee. 2002. Attenuation of human –to-pig xenogenic
cellular proliferation and Th1 response by expressing the human MHC
II, DQ, exogenes. 7th Congress of the Asian Society of
Transplantation.
New Delhi
,
India
. p.93.
Tu,
C. F.
2002. The progress of transgenesis in xenotransplantation. In: Recent
Advance in Organ Transplantation. 台中榮民總醫院成立20週年,器官移植新知研討會,台中。(Invited
lecture)
Chen,
I. C., M. S. Leu, C. K. Yang, L. L. Ho, C. C. Chen, and C. F.
Tu. 2002. Analysis of germ-line transmission rate and
stability of human leucocyte antigen-DR (A1+B1) genes in double
transgenic mice. J. Chin. Soc. Anim. SCI. 31: 132.
吳信志、李章源、陳全木、翁仲男、楊平政、杜清富、楊向中及鄭登貴。2002。複製豬技術再農業及生醫之應用。中華民國實驗動物學會。
PP. 14-16。(Invited
lecture)
Wu,
S. C., C. M. Chen, Jangwon. Lee, S. P. Lin, K. B. Choo, C. N. Weng, P.
C. Yang, C. F. Tu, X. Yang, W. T. K. Cheng. 2002. Generation of
double-genes transgenic pigs and their cloning. International
Symposium on Agricultural Biotechnology (ISAB). PP.64-65。
Wu,
S. C., C. J. Lin, C. F. Tu, S. P. Lin, S. R. Wang, C. H. Mao,
C. M. Chen, K. B Choo, W. T. K. Cheng. 2002. Recent advances in
studies related to generation of transgenic farm animals in
Taiwan
. International Symposium on Agricultural Biotechnology (ISAB).
PP.59-61.
Tu C. F., J. M Lee., C. K. Yang, H. C. Tai, B. T. Wang, L. L. Ho,
I. C. Chen, C. J. Lee. 2003. The integration and expression in
transgenic pigs for hDAF/hHO-1 double genes. Xenoransplantation 10:
503 (S13.3).
Wang,
B. T., C. F. Tu, L.
J. Hsieh, H. C. Tai, Y. L. Chiu, S. J. Lee, J. M. Lee., K. Tsuji and
C. J. Lee. 2003. Detection of
HLA transgenes in pigs by FISH for study of human xenotransplantation.
Xenoransplantation 10: 527 (P15.05).
Lee,
J. M, C. F. Tu, H. Y. Hung, H. S. Tsau, K. Tsuji, R. P. Hsieh, H. C. Tai, C. N. Weng, Y.
C. Lee, C. J. Lee.
2003. Reduction of human-to-pig
xenogenic cellular proliferation by expressing the human MHC II DR
exogenes on porcine cells.
8th Congress of
Asia
Transplantation.
Malaysia
.
Huang,
S. Y., Y. H. Chen, L. L. Ho and C.
F. Tu. 2004. Study on protein expression of lymphocyte
in HLA transgenic pigs by a proteomic approach. 3rd
International Proteomics Conference (IPC’03) and 1st
Taiwan
Proteomics Conference Joint Meeting of AOHUPO 2004.
Taipei
,
Taiwan
, May 14-17, 2004. P-89.
Lin, C. J., C. K. Yang, C. H. Yen,
I.
C. Chen and C. F. Tu. 2004. Production of Hirudin in
transgenic mice milk. In: New dimensions and challenges for
sustainable livestock farming. Vol. II, pp. 172-174.11th AAAP
Congress, 5-9th Sept. 2004,
Kuala Lumpur
, Malaysian.
Tu,
C. F.,
K. F. Huang,
I.
C. Chen, C. J. Lin, S. C. Wu. 2004. Application of Real Time PCR to
Rapidly Screen Hirudin Transgenic Piglets. In: New dimensions and
challenges for sustainable livestock farming. Vol. II, pp. 175-177.
11th AAAP Congress, 5-9th Sept. Kuala Lumpur, Malaysian.
杜清富、鄭登貴。基因轉殖家畜禽研發現況與管理法規。基因轉殖動物產品推廣利用消費者認知研討會
pp.1-4。台灣動科技研究所主辦。(Invited
lecture)
林寅申、劉明薰、陳逸仲、顏重河、杜清富、楊平政。2004。基因轉殖鼠乳液中血蛭素之表現分析。中畜會誌 33增刊:284。
李坤雄、張惠溶、王慧雯、張新傑、鍾智揚、杜清富、2004。利用微試管共同培養胚幹細胞與去除透明帶胚可以有效產製具性腺遺傳能力小鼠。中畜會誌33:69 (摘要)。
Tu, C. Fu, J. M. Lee, C. C. Wang, C. L. Chen, D. Wang, T. S. Yang, H. C. Tai,
C. K. Yang, L. L. Ho, I. C. Chen, B. T. Wang, Y. L. Tseng, K. Tsuji
and C. J. Lee. 2004. The Progress of Genetic Modification Pigs Organs
for Human Xenotransplantation. 7th Annual Meeting of The
Transplantation Society of
Taiwan
. pp. 16-17.,
Taipei
,
Taiwan
. (Invited lecture)
Tu,
C. F.,
J. M. Lee, W. T. K. Cheng, P.
C. Yang, D. Wang, T. S. Yang, H. C. Tai, S. C. Wu, B. T. Wang, Y. L.
Tseng, C. N. Weng, K. Tsuji and C. J. Lee. 2004. The
Application of GM Farm Animal in Biomedical Science. International
Biotech Conference & Exhibition. Nov. 25-27. 2004.
National
Kaohsiung
Marine
University
,
Kaohsiung
,
Taiwan
. (Invited
lecture)
Huang,
S. Y., Y. H. Chen, Y. F. Chiou, J. H. Lin, W. T. K. Cheng, S. C. Wu,
P. C. Yang, C. F. Tu*.
2005. Analysis of the differential protein expression in mammary gland
of human factor IX transgenic pigs using two dimensional gel
electrophoresis and mass spectrometry. 2005台灣質譜學會-華人質譜學術交流研討會.
Tu, C. F., C. Kuo, J. Juang*.
2005. Effects of heme oxygenase-1 transgenic islets on
transplantation. 10th International Pancreas and Islet Transplantation
Association (IPITA) held in
Geneva
on May 4-7, 2005.
Tu, C. F*., C. C. Wang, I. C. Chen, L. C. Chen, S. P. Sun, L. L.
Ho, C. g-C. Hsiao. 2005. Generation of hHO-1/GFP transgenic animals
for xenotransplantation of tissues and cells. 8th International
Xenotransplantation Congress.
10-14th Sept. 2005
.
Goteborg
,
Sweden
. P3:7, p.402.
Yang, T. S., H.C. Tai, C.
F. Tu, D. Wang, J. M. Lee, B. T. Wang, Y. L. Tseng, P. D. Lee
and C. J. Lee. 2005.
Effects of temperature on the perfusion of human blood
into isolated kidney of hDAF transgenic pigs. 8th International
Xenotransplantation Congress. 10-14th Sept. 2005.
Goteborg
,
Sweden
. P9:6, p.413.
杜清富、劉學陶。2005。我國首座基因轉殖家畜隔離田間試驗場設施介紹。基因轉殖動物藥用蛋白質產品研發及規範研討會(台灣動科技研究所主辦)。pp.52-57。
杜清富、吳信志、孫淑萍、陳逸仲、黃紹怡、高兆志、李世偉、林恩仲、林劭品、王仕蓉、楊平政、翁仲男、朱廣邦、鄭登貴。2005。人類凝血第九因子子暨豬乳鐵蛋質雙基因轉殖豬性腺傳承之基因穩定分析。基因轉殖動物藥用蛋白質產品研發及規範研討會(台灣動科技研究所主辦)。pp.99-100(摘要)。
林寅申、顏重河、杜清富、楊平政。2005。基因轉殖鼠乳液中血蛭素純化及分析。基因轉殖動物藥用蛋白質產品研發及規範研討會(台灣動科技研究所主辦)。pp.102(摘要)。
杜清富、黃三元、林恩仲、陳逸仲、何玲玲、陳玉惠、孫淑萍、邱玉芳、陳建宏、劉明薰、鍾孟婷、張雲喬、連雯慈。2005。基因轉殖家畜禽隔離田間試驗配套功能實驗室:生物技術實驗室-CNLA認證編號1734。基因轉殖動物藥用蛋白質產品研發及規範研討會(台灣動科技研究所主辦)。pp.114(摘要)。
陳建宏,石力,連雯慈,劉明薰,杜清富,李坤雄。2005。不同激活方式對產製體細胞核轉置複製小鼠之影響。中華實驗動物學會94年度會員大會暨學術研討會論文集,p.
30。
石力*、陳建宏、連雯慈、劉明薰、杜清富、李坤雄。2005。不同品系體細胞核移置小鼠胚之激活、培養及分娩。中畜會誌
34(增刊):105。
林鈺齊*、劉世華、張慧玫、杜清富、鄭登貴。2005。豬胚(18日齡)與胎(24日齡)mRNA表現之差異。中畜會誌
34(增刊):148。
陳建宏*、連雯慈、黃紹怡、高兆志、陳逸仲、劉明薰、林之任、石力、張惠溶、李坤雄、杜清富、吳信志。2005。以耳朵成纖維母細胞複製優良種公豬。中畜會誌
34(增刊):183。
林寅申*、顏重河、杜清富、楊平政。2005。基因轉殖鼠乳液中血蛭素純化及分析。中畜會誌
34(增刊):275。
C. F. Tu,
I. C. Chen, L. L. Ho, S. Chu, C. H. Chen, C. K. Yang and C. H. Yen.
2006. Germline Transmission and Genetic Characterization of Hirudin
Transgenic Pigs. 12th AAAP Congress, 18-22th Sept. Busan, Korea. Abs.
p.539.
Chen, C. H., S. Chu, Y. S. Lin, C. H. Yen, T. T. Huang and C. F.
Tu. 2006. Ovine Beta-Casein Promoter Ectopically Express
Hirudin in Transgenic Mice. 12th AAAP Congress, 18-22th Sept. Busan,
Korea. Abs. p.548.
Tu, C. F.,
W. D. Fang, C. H. Yen, L. L. Ho, S Chu, C. H. Chen, E. C. Lin, S. C.
Wu, W. T. K. Cheng and P. C. Yang. 2006. The Reproductive Performance
of a Dual Transgenic Sow with Homozygote hFIX/pLf.
基因轉殖豬乳液中水蛭素之大量純化。轉殖性動植物生產人用藥品及生物相似性藥品法規研討會。P.119.
林寅申、顏重河、杜清富、楊平政。2006。基因轉殖豬乳液中水蛭素之大量純化。轉殖性動植物生產人用藥品及生物相似性藥品法規研討會。p.124。
朱森、顏重河、林寅申、何玲玲、陳建宏、劉明薰、連雯慈、吳秋萍、杜清富。2006。山羊酪蛋白啟動子/水蛭素(Beta-Casein/Hirudin)在基因轉殖豬異位表現。中畜會誌
35(增刊):183。
江柏輝、楊天樹、杜清富。2006。基因轉殖母豬泌乳期之血液性狀變化。中畜會誌
35(增刊):196
。
Huang, S.Y., J. H. Lin,
Y. H. Chen, Y. F. Chiou, S. C. Wu, W. T. K. Cheng, C. F. Tu,
2007.
Comparison of protein
expression in mammary gland from different lines of human factor IX
transgenic and non-transgenic pigs using a proteomic
approach. 2007年第四屆台灣質譜年會暨國際學術交流研討會(台南成功大學,96年6月29-30日)。會議手冊
P. 45.
Lee, J. M., C. F. Tu, H. C. Tai, N.
K. Chou, C. N. Weng, Y. C. Lee, C. J. Lee, P. H. Lee. 2007.
The impacts of human ABO blood groups on human
xenoreactive antibody-mediated cytotoxicity and the protective effect
of human decay accelerating factors (hDAF) exogene on the swine
endothelium.
Xenotransplantation 14: 455 (PC311).
Tu, C. F.,
H. C. Tai, C.-m. Chen, T. T. Hung, J. M. Lee, T. S. Yang, C. H. Chen,
Y. L. Tseng, N. K. Chou, P. H. Lee. 2007.
Human Leukocyte Antigen-DR Matching Improved Skin Graft From
Ttansgenic Pigs to Accommodate in SCID Mice Reconstructed with Human
Peripheral Blood Mononuclear Cells.
Xenotransplantation 14: 460
(PD414).
Tai, H. C., C. F. Tu,
L. L. Ho, Y. C. Chao, N. K. Chou, J. M. Lee, T. S. Yang, P. H. Lee, Y.
B. Tang, K. J. Chang.
2007. Long-Term Survival of HLA-DR Pig Skin
in SCID Mice after Reconstitution with Human PBMC and Short-Term
Immunosuppression.
Xenotransplantation 14: 458 (PD406).
Yang, T. S., C. F.
Tu, H. C. Tai, D. Wang, Y. L. Tseng, N. G. Chou, J. M. Lee and
P. H. Lee. 2007. Effects of expression level of human DAF alone and
with human HO-1 in transgenic pig kidney ex-vivo perfused with freshly
collected human blood. Xenotransplantation 14: 382 (106.2).
Huang, S. Y. and
C.
F. Tu*. 2007. Application of proteiomics in monitoring the
proteome of transgenic pig. p. 24.
台灣蛋白體學會年會暨國際研討會(台南成功大學,
96年12月4-5日)
Huang, S. Y.,
J. H. Lin, Y. H. Chen, Y. F. Chiu, Shih-Hua Teng, S. C. Wu, W. T. K.
Cheng, C. F. Tu*. Differential protein expression in
livers from human Factor IX transgenic and non-transgenic pigs using a
proteomic approach. p. 107.
台灣蛋白體學會年會暨國際研討會(台南成功大學,
96年12月4-5日)
Tu, C. F.,
H. C. Tai, T. S. Yang, J. M. Lee, Y. L. Tseng, C. k. Chuang, N. K.
Chou, C. Y. Yang, C. N. Weng, P. H. Lee.
2008. Development of Transgenic Pigs for Xenotransplation. Taipei
International Organ Transplantation Forum (器官移植40週年暨紀念李俊仁教授學術研討會),
Apr. 25-26th. NTUH, Taipei, Taiwan.
Tu, C. F.,
H. C. Tai, T. S. Yang, J. M. Lee, Y. L. Tseng, C. k. Chuang, N. K.
Chou, C. Y. Yang, C. N. Weng, P. H. Lee.
2008. Development of Genetic Modification Pigs for Xenotransplation.
行政院農業委員會畜產試驗所50週年所慶,生理學術研討會。97年5月22~23日,台南新化,台灣。
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杜清富。
2000。生物技術與養豬產業。台灣養豬科學研究所編:二十一世紀養豬領導班
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鄭登貴、杜清富、吳信志,
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pp.153-178。現代學術研究基金會。台北。(ISBN
957-99963-6-9)
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杜清富。2003。利用反轉錄病毒載體法產製基因轉殖動物。動物基因轉殖技術與實驗
pp58-70。教育部顧問室「生物技術科技教育改進計畫」。(ISNB
957-01-7605-9)
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杜清富、鄭登貴。2003。基因轉殖豬之產製。動物基因轉殖技術與實驗
pp172-188。教育部顧問室「生物技術科技教育改進計畫」。(ISNB
957-01-7605-9)
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杜清富。2004。「基因轉殖家畜禽」生產醫藥蛋白質。科技報導
270(6):16-19。
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杜清富。2004。國內外家畜禽基因轉殖科技之應用與發展。農科新世紀-農業生物科技園區專訊
1:
36-40。
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杜清富。2004。生命的延續-異種移植。「生命科技與生命倫理」。玄奘大學。
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