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                               姓名:林志鴻

                               職稱:副研究員

                               地址:苗栗縣竹南郵政23號信箱/苗栗縣竹南鎮頂埔里科東二路

                          52號

                              電話:037-585796

                              傳真:037-585829

                               E-MAIL:jhl01@mail.atit.org.tw

 

         

 

    學歷:

                          國立臺灣大學獸醫所博士

                          國立中興大學獸醫所碩士

    經歷:

                           台灣動物科技研究所 副研究員

    專長:

                             1、臨床心臟學

                             2、心臟形態學

                             3、動物生理學

    研究興趣:

                              1、豬肥厚性心肌病之臨床研究

                              2、預防心肌缺血與再灌流傷害之保護劑研發

                               3、心血管基質發生纖維化之機制

    歷年發表報告:

            (A) 論文

1.          林志鴻,王耀宏,李文權,李相台,林凱元,陳惠卿,林寶雪,黃琇琴,彭兆昌,毛仁淡,楊平政,朱瑞民。利用無特定病原豬建立缺血心肌保護機制之研究模式。中華獸醫誌,24:227-235. 1998

2.          吳鍾政,黃三元,鄒會良,楊平政,林志鴻,林育興。臺灣蘭嶼小耳豬作為生物醫學實驗動物之探討。科學農業,46:156-162. 1998

3.          Lin JH, Chu RM, Yang, PC, Weng CN, Lin PH, Liu SK and Mao SJT. Influence of age on the electrocardiographic waves in Taiwan Lan-Yu miniature pigs. Contemporary Topics Lab Anim Sci. 38: 35-40. 1999.

4.          Huang HC, Lee WC*, Lin JH, Huang HW, Jian SC, Mao SJT, Yang PC, Huang TY, Liu YC. Molecular cloning and characterization of porcine cDNA encoding a 90-Kda heat shock protein and its expression following hyperthermia. Gene, 226:307-315. 1999. (SCI)

5.          Huang SY, *Tsou HL, Chiu YT, Wu JJ, Lin JH, Yang PC, Liu SK. Statistical method for characterization of hypertrophic cardiomyopathy by morphologic and pathologic measurements in pigs (Sus scrofa domestica) Lab Ani Sci. 49:276-282. 1999. (SCI)

6.          李文權、楊平政、林志鴻。豬肥厚性心肌病研究成果。科學發展月刊,27:1421-1430. 1999

7.          Chu RM, Sun TJ, Yang HY, Wang DG, Liao KW, Chung TF, Lin CH, Lee WC. Heat shock  proteins in canine transmissible venereal tumor. Vet. Immunol. Immonopathol. 82:9-21. 2001. (SCI)

8.          Huang SY, Lin JH, Lin EC, Yang PC, Tsou HL. Effects of season, breed, sex, and sire family on cardiac morphology by echocardiographic examination in pigs (Sus scrofa domestica). Comp. Med. 51:545-549. 2001. (SCI)

9.          King YT, Lin CS, Lin JH, Lee WC. Whole-body hyperthermia-induced thermotolerance is associated with the induced of heat shock protein 70 in mice. J. Experi. Biol. 205:273-278. 2002. (SCI)

10.      Shyu JJ, Cheng CH, Erlandson RA, Lin JH and Liu SK. Ultrastructure of intramural coronary artery in the pig with hypertrophic cardiomyopathy. Cardiovasc. Pathol. 11:104-111. 2002. (SCI)

11.      Lin JH, Huang SY, Lee WC, Liu SK and Chu RM. Echocardiographic features of pigs with spontaneous hypertrophic cardiomyopathy. Comp. Med. 52:238-242. 2002. (SCI)

12.      Huang HC, Tsay CC, Yu JS, Lin JH, Huang SY, Fang WT, Liu YC, Tzang BS and  Lee WC. Purification and characterization of porcine testis 90-kDa heat shock protein (HSP90) as a substrate for various protein kinase. Journal Protein Chemistry 21(2):111-121. 2002. (SCI)

13.      Lee WC, Hsiao HC, Wu YN, Lin JH, Lee YB, Fung HP, Chen HH, Chen YH and  Chu RM. Serum C-reactive protein in daily herda. Canadian Jouranl of Veterinary Research, 67:102-107. 2002. (SCI)

14.      陳欣欣,林志鴻,鄒會良,翁仲男,朱瑞民。2-7月齡生長豬隻之血清急性期蛋白質濃度。臺灣獸醫誌,19:257-265. 2003。

15.      Chen HH, Lin JH, Fung HP, Ho LL, Yang PC, Lee WC, Lee YP and Chu RM. Serum acute phase proteins and swine health status. Canadian Jouranl of Veterinary Research, 67:283-290 2003. (SCI)

16.      Chen MY, Tu CF, Huang SY, Lin JH, Tzang BS, Tsou HL, Hseu TH, Lee WC. Augmenting thermotolerance in primary skin fibroblasts from a transgenic pig with overexpressed porcine HSP70.2. Asian-Australia Journal of Animal Sciences, 18:107-112. 2005. (SCI).

17.    Huang SY, Lin JH, Chen YH, Chuang CK, Lin EC, Huang MC, Sun HS, Lee W.C. A reference map and identification of porcine testis proteins using two-dimensional gel electrophoresis and mass spectrometry. Proteomics 5:4205-4212. 2005.

18.      Huang SY, Tam MF, Hsu YT, Lin JH, Chen HH, Chuang CK, Chen MY, King YT, Lee WC. Developmental changes of heat-shock proteins in porcine testis by a proteomic analysis. Theriogenology. 64:1940-1955. 2005. (SCI)

19.      Huang SY, Lin JH, Chen YH, Chung CK, Chen MY, Chen HH, Lee WC. Analysis of chicken serum proteome and differential protein expression during development in singe-comb White Leghorn hens. Proteomics. 6:2217-2224. 2006. (SCI)

20.   Liou, M.L., S.Y. Huang, J.H. Lin, Y.C. Liu, W.C. Lee*, 2007. Association of serum protein levels with egg productivity in Taiwan red-feathered country chickens. Anim. Reprod. Sci. 100:158-171.

 

        (B) 摘要

1.      Huang, SY, Tsou HL, Lin JH, Wu JJ, Lin PH, Lin EC, Yang PC, Liu SK. Effects of breed, sex, and sire family on echocardiographic measurements in pigs. 中華獸醫誌 24(Suppl.):66. 1998.

2.      Mao SJT, Wu JCH, Sun TJ, Lin JH, Lin CS, Yang PC, Chu R, Shvy JYJ, Chien S.  Remodeling and characteristics of the intimal proliferation of balloon injured artery: a porcine model of restenosis. Atherosclerosis, 136(Suppl):S52. 1998.

3.      Wu JCH, Mao SJT, Lin CS, Lin JH, Jin G, Shyy YJ, Chien S. Application of gene therapy on angioplasty-induced restenosis. The 1998 International Symposium of Comparative Medicine in Cardiovascular Diseases, ROC, p26. 1998.

4.      Huang HC, Lee WC, Lin JH, Huang HW, Jian SC, Mao SJT, Yang PC, Liu YC. Molecular cloning and characterization of porcine cDNA encoding a 90-kD heat shock protein whose expression is induced following hyperthermia. The 1998 International Symposium of Comparative Medicine in Cardiovascular Diseases, ROC, p32. 1998.

5.      Tsou HL, Huang SY, Lin JH, Lin EC, Wu JJ, Chiu YT, Yang PC, Mao SJT, Liu SK. Development of pig model for hypertrophic cardiomyopathy : a status report. The 1998 International Symposium of Comparative Medicine in Cardiovascular Diseases, ROC, p38. 1998.

6.      Lin, JH; Lin, PH; Huang, SY; Wu, JJ; Mao, SJT; Yang, PC; Chu, R. Echocardiograpgic assessment of left ventricular mass in pigs with hypertrophic cardiomyopathy. The 1998 International Symposium of Comparative Medicine in Cardiovascular Diseases, ROC, p39. 1998.

7.      Huang, S. Y., Tsou H.L., Lin J.H., Wu J.J., Lin P.H., Lin E.C., Yang P.C., and Liu S.K., Effects of breed, sex, and sire family on echocardiographic measurements in pigs. 中華獸醫誌 24 (Suppl.): 66. 1998.

8.      Huang H.C., Lee, W.C., Lin, J.H., Huang H.W., Jian S.C., Mao, SJT., Yang P.C., Huang T.Y., Liu, Y.C. Molecular cloning and characterization of porcine cNDA encoding a 90-kDa heat shock protein and its expression following hyperthemia. America Society for Biochemistry and Molecular Biology. Annual Meeting and Satellite Meetings. A25, LB117. 1998.

9.      Huang, S.Y., Y.T. Hsu, Y.T. King, J.H Lin, S.L. Lee, Y.H. Kuo, and W.C. Lee, Alteration of heat shock proteins in porcine testis before and after sexual maturation. 中華獸醫誌 25(Suppl.):54. 1999.

10.  蕭火城、林志鴻、林家賢、陳欣欣、李文權、朱瑞民。台灣北部地區乳牛血清中C-反應蛋白質濃度之調查與分析。中華獸醫誌,25(增刊): 55, 1999

11.  Lin, J.H., S.Y. Huang, S.K. Liu, W.C Lee, and R. Chu, Echocardiographic assessment in pigs with spontaneously occurring hypertrophic cardiomyopathy. The 7th World Congress on Heart Failure - Mechanisms and management, July 9-12, Vancouver B.C., Canada. J. Heart Failure 6:44. 2000.

12.  Lin, J.H., M.L. Hou, W.C Lee, and R.M. Chu. Changes of matrix metalloproteinases in neointima of restenosis. The 11th Congress of the Federation of Asian Veterinary Associations, Nov. 27-29, Taipei, ROC. p.301. 2000.

13.  Lin, J.H., W.C Lee, R.M. Chu and S.K. Liu. Echocardiographic assessment in pigs with spontaneously occurred hypertension. The 11th Congress of the Federation of Asian Veterinary Associations, Nov. 27-29, Taipei, ROC. p.399. 2000.

14.  Huang, S.Y., H.L. Tsou, J.H. Lin, E.C. Lin, P.C. Yang, and S.K. Liu, Heritability estimates of cardiac morphology by echocardiographic examination in pigs. The 11th FAVA Congress, November 19-22, Taipei, Taiwan, Republic of China. Proceedings: 287. 2000.

15.  黃三元,林志鴻,金悅祖,林恩仲,鍾孟婷,王旭川,鄒會良,李文權熱緊迫蛋白質70.2基因啟動子區多態型對豬隻熱緊迫反應之影響。中畜會誌 29(Suppl.):174, 2000。

16.  黃三元,譚鳴輝,,林恩仲,林志鴻,宋秀麗,鍾孟婷,李文權應用基質輔助雷射解離/離子化質譜儀確認公豬睪丸蛋白質中畜會誌 30:171 2001

17.  陳欣欣、林志鴻、何玲玲、李文權、朱瑞民。上市肉豬健康狀態與血清中Haptoglobin 濃度之關係。中華獸醫年會,p672001

18.  林志鴻、李文權、黃三元、朱瑞民、劉錫光。豬肥厚性心肌病中左心室功能與心肌病變之關係。中華獸醫年會,p682001

19.  宋秀麗、林志鴻、曾博修、李文權、黃三元。。豬精原細胞之分離及蛋白質樣式分析。 中畜會誌 31(4):1632002

20.  Song, H.L, J.H. Lin, Y.J. Chou, C.T. Liang, and S.Y. HuangIsolation and proteomic analysis on porcine Sertoli cell。中華民國獸醫學會暨台灣省畜牧獸醫學會九十二年度聯合學術論文研討會,2003

21.  Huang, S.Y., M.F. Tam, J.H. Lin, E.-C. Lin, H.L Song, M.C. Huang, H.S. Sun and W.C. Lee, A Reference Map and Identification of Porcine Testis Proteins Using Two-dimensional Gel Electrophoresis and Mass Spectrometry. 中華民國獸醫學會暨台灣省畜牧獸醫學會九十二年度聯合學術論文研討會2003.

22.  邱玉芳、莊景凱、林志鴻、周佑吉、黃三元。2004。豬Sertoli細胞永生化細胞株之建立及其對Jurkat T細胞進行細胞凋亡之保護效果。中畜會誌 33 (Suppl.):185  

23. 劉明麗、林志鴻、莊景凱、黃三元、劉銀樟、黃次洋、李淵百、李文權*2004。禽類產蛋生物路徑分析。科學農業 52:244-254

24. Lee W.C., S.Y. Huang, J.H. Lin, and M.Y. Chen*. 2004. Studies on relationship between heat shock protein 70 and economical traits in pig. International Symposium on Tropical Agriculture and Agro-Biotechnology. December 7th-9th, Ping-Dong, Taiwan, R.O.C.

25.  Huang, S.Y., Y H. Chen, Y.F. Chiou, J.H. Lin, W.T.K. Cheng, S.C. Wu, P.C. Yang, C.-F. Tu. 2005. Analysis of the differential protein expression in mammary gland of human factor IX transgenic pigs using two dimensional gel electrophoresis and mass spectrometry. 2005年華人質譜學術交流研討會,94616-17日,中興大學,台中市。

26.  Huang, S.Y., J.H. Lin, W.C. Lee, C.-k. Chuang, Y.H. Chen, M.T. Chung, E.-C. Lin, M.C.    Huang, and H.S. Sun, 2006. Differential protein expression during postnatal development of   porcine testis. Joint 6th Human Genome Organization (HUGO) Pacific Meeting & 7th Asia-Pacific Human Genetics Conference (HUGO-AP 2006), March 6-10, Academia Scinica, Taipei, Taiwan.  

27. Chiu, Y.F., C.-k. Chuang, S.H. Chiou, Y.H. Fan, J.H. Lin, and S.Y. Huang, 2006. Cloning and expression of a testis-specific hsp70 gene in porcine testis. 12th AAAP Anim. Sci. Congr., September 18-22, Busan, Korea. Congress Proceedings CD C09-PP-011.

28. Huang, S.Y., J.H. Lin, C.-k. Chuang, S.H. Chiou, Y.F. Chiu, Y.H. Chen, M.T. Chung, W.D. Fang, and H.L. Tsou, 2006. A reference map and identification of porcine lymphocyte proteins using using 2-DE and MS. 12th AAAP Anim. Sci. Congr., September 18-22, Busan, Korea. Congress Proceedings CD C10-PP-017.

29. Huang, S.Y., J.H. Lin, Y.H. Chen, Y.F. Chiou, S.C. Wu, W.T.K. Cheng, C.F. Tu, 2007. Comparison of protein expression in mammary gland from different lines of human factor IX transgenic and non-transgenic pigs using a proteomic approach. 2007年第四屆台灣質譜年會暨國際學術交流研討會,96629-30日,成功大學,台南市。會議手冊 P. 45.

30. 高炳煌、朱一民、黃木秋、楊國泰、邱繡河、范怡馨、陳明玉、林志鴻、莊景凱、黃三元、李文權2007利用精細胞熱緊迫模式發現與公豬精液品質相關之生物標記。中畜會誌 36(增刊):209

31. Huang, S.Y., J.H. Lin, Y.H. Chen, S.H. Teng, S.C. Wu, W.T.K. Cheng, and C.F. Tu, 2007. Differential protein expression in livers from human factor IX transgenic and non-transgenic pigs using a proteomic approach. Taiwan Proteomics Society International Conference 2007, December 4-5, National Cheng-Kung University, Tainan, Taiwan. Program Book p.107.

32. Chun Yu, Shu-Fen Chen, Jer-Junn Lu, Jing-Liang Yu, Chih-Hung Lin, Chii-Wann Lin. The studies of pressure ulcer degree and environmental factors of skin on animal model of pigs.2007生物醫學工程科技研討會暨國科會醫學工程學門成果發表會論文集.(台中逢甲大學):P1090-1093.

33. 林志鴻,黃科志,林泰勇,翁炳國,陳順林,張志清,葉春台,陳欣欣,陳宛宜,林寶雪,邱滄賈,吳憲明。2007。膠囊內視鏡動物活體測試技術平台之建立。中華民國獸醫學會暨台灣省畜牧獸醫學會九十六年度聯合年會暨學術論文發表會(台中中興大學):69。

34. 林志鴻,林明煊,陳明玉,林寶雪,李文權。苦蘵水萃物之安全性評估。2007。中華實驗動物學會第一次會員大會暨學術研討會論文集(台北中央研究院):48。

                                                                             

             專利:

 

序號

名稱

發明人

國別

案號

專利期間

1

篩選高產蛋禽類之方法

陳欣欣、李文權、林志鴻及莊景凱

中華民國

095102134

申請中

2

篩選高產蛋禽類之方法

陳欣欣、李文權、林志鴻及莊景凱

大陸

2006100001699.9

申請中

               3       Tzang, B.S., C.F. Tu, W.C. Lee, M.Y. Chen, S.Y. Huang, and J.H. Lin. Transgenic pig containing 

                    heat shock protein 70 transgene.  USA patent No. US 7,115,796 B2.

 

                技術移轉:

                    申請中專利『篩選高產蛋禽類之方法』已授權高首企業有限公司,相關技術移轉中。

                                                                                                                                                                                          2008/02/14