學歷

        清華大學化學工程學系        學士

        清華大學分子生物研究所    碩士

        清華大學生命科學研究所    博士

  經歷

        清華大學生命科學研究所

        博士後副研究員 1990/2~1990/7

                                 1992/6~1994/2

        Department of Biochemistry and 

        Molecular Biology

        The University of Texas, 

        M. D. Anderson Cancer Center

        Postdoctoral fellow 1994/9~1996/8

        中央研究院生醫所

        博士後研究員 1996/10~2002/8

        臺灣動物科技研究所

        生物科技組  副研究員 2002/9~

  I. Regular papers:

Juang, J.-k., and Liu, H.-J. (1987), The effect of DMSO on natural DNA conformation in enhancing transcription, Biochem. Biophys. Res. Commun., 146: 1458-1464.

Juang, J.-k., Huang, H.-w., and Liu, H.-J. (1989), A new compound, withangulatin A, promotes type II DNA topoisomerase-mediated DNA damage, Biochem. Biophys. Res. Commun., 159: 1128-1134.

Huang, H.-w., Juang, J.-k., and Liu, H.-J. (1992), The recognition of DNA cleavage sites by porcine spleen topoisomerase II, Nucleic Acids Res., 20: 467-473.

Mao, C.-A., Wikramanayake, A., Gan, L., Chuang, C.-k., and Klein, W. H. (1996),  Altering cell fates in sea urchin embryos by overexpression SpOtx, an orthodenticle-related protein, Development, 122: 1489-1498.

 Chuang, C.-k., Wikramanayake, A., Mao, C.-A., Li, X.-T., and Klein, W. H. (1996), Transient appearance of Strongylocentratus purpuratus Otx in micromere nuclei: cytoplasmic retention of SpOtx possibly mediated through an a-actin interaction, Developmental Genetics, 19: 231-237.

Li, X.-T., Chuang, C.-k., Mao, C.-A., Angerer, L. M., and Klein, W. H. (1997), Two Otx proteins generated from multiple transcripts of a gene in Strongylocentratus purpuratus, Developmental Biology, 187: 253-266.

Chen, S. S.-L., Lee, S.-F., Hao, H.-j., and Chuang, C.-k. (1998), Mutations in the leucine zipper-like heptad repeat sequence of human immunodefficiency virus type 1 gp41 dominantly interfere with wild-type virus infectivity, J. Virol., 72: 4765-4774.

Chuang, C.-k., Lee, S.-F., and Chen, S. S.-L. (1999) Conferral of an antiviral state to CD4+ cells by a zipper motif envelope mutant of the human immunodefficiency virus type 1 transmembrane protein gp41, Human Gene Therapy, 10: 2381-2395.

Chen, S. S.-L., Lee, S.-F., Chuang, C.-k., and Raj, V. S. (1999), Trans-dominant interference with human immunodefficiency virus type 1 replication and transmission in CD4+ cells by an envelope double mutant, J. Virol., 73: 8290-8302.

Hu, H.-M., Chuang, C.-k., Lee, M.-j., Tseng, T.-c., and Tang, K. T. (2000), Genomic organization and chromosomal localization of a third mouse Aurora-related kinase gene, AIE1, DNA Cell. Biol., 19: 679-688.

Tang, C.-J. C., Chuang, C.-k., Hu, H.-M., and Tang, K. T. (2001), The zinc finger domain of Tzfp binds to the tbs motif located at the upstream flanking region of the Aie1 (Aurora C) kinase gene, J. Biol. Chem., 276: 19631-19639.

Chuang, C.-k., Hu, H.-M., Liu, P.-c., Chen, J.-y., and Tang, K. T. (2002~), The Aurora C kinases are encoded by clustered multi-copy genes, (paper in preparation)

Chuang, C.-k., Yoo, Y.-c., Chen, S. H., and Tang, K. T. (2002~), An improved Cre encoded vector to remove floxed neo cassette from chromosome in ES cells, (paper in preparation)

Chuang, C.-k., and Tang, K. T. (2002~), Establishment and characterization of murine primary apermatogonia cell lines with pluri-potency of trans-differentiation, (paper in preparation)

Chuang, C. k., H. M. Hu, P. C. Liu, J. Y. Chen and T. K. Tang.*(2004). The Aurora kinases C is encoded by clustered multi-copy genes, Genetics, (revised)

  II. Conference paper:

1.

Klein, W. H., Mao, C.-A., Gan, L, Chuang, C.-k., and Wikramanayake, A. (1995), Manipulating cell fates in sea urchin embryo (in "Invertebrate Reproduction and Development 7th ICIR Proceedings")

  III. Patent:

回首頁

實驗室簡介